Probing Dynamics of 14-3-3:
نویسندگان
چکیده
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منابع مشابه
14-3-3 Regulates Actin Dynamics by Stabilizing Phosphorylated Cofilin
The functionality of the actin cytoskeleton depends on a dynamic equilibrium between filamentous and monomeric actin. Proteins of the ADF/cofilin family are essential for the high rates of actin filament turnover observed in motile cells through regulation of actin polymerization/depolymerization cycles. Rho GTPases act through p21-activated kinase-1 (Pak-1) and Rho kinase to inhibit cofilin ac...
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One of the most striking 'rags to riches' stories in the protein world is that of 14-3-3, originally identified in 1967 as merely an abundant brain protein. The first clues that 14-3-3 would play an important role in cell biology came almost 25 years later when it was found to interact with various proto-oncogene proteins and signaling proteins. The subsequent identification of 14-3-3 as a phos...
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ژورنال
عنوان ژورنال: Translation
سال: 2023
ISSN: ['2469-6706']
DOI: https://doi.org/10.46570/utjms.vol11-2023-733